Cannabis
Cannabis has biological properties including immunomodulation and effects on excitototoxicity that suggest it could be useful in ALS. Evidence from small, non-randomized, unblinded animal studies suggest that it could potentially…
Mechanism: C
Grade C: Theoretically and plausibly acts on an ALS-relevant mechanism in humans
Coconut Oil
Coconut oil has plausible mechanisms for use in ALS involving raising ketone bodies and lipid levels. Ketogenic and high fat diets may have helped slow motor neuron loss in small…
Mototab
Given the lack of demonstrated effectiveness, and the above-documented concerns about product safety and supplier identity and reliability, ALSUntangled does not support the use of mototab for amyotrophic lateral sclerosis…
Bee Venom
In our opinion, BV has biological effects that could potentially be useful in ALS. Two ALS-animal studies in which BV was injected into an unusual anatomic location showed positive effects…
NuTech Mediworld
Now 26 months old, ALSUntangled (www.alsuntangled. org) investigates alternative and off-label treatment options in ALS using social networking tools. Our twitter and NING memberships continue to grow. To date we…
Luteolin and Lutimax
In summary, luteolin is an interesting naturally occurring bioflavinoid that has been shown to have a myriad of functions in various models that could potentially be useful in slowing progression…
Spirulina (blue green algae) as a treatment for ALS
At this time, ALSuntangled finds no evidence that Spirulina is effective for ALS and there appear to be real and theoretical toxicities that patients with ALS may encounter with it.…
Read more Spirulina (blue green algae) as a treatment for ALS
Hyperimmune Goat Serum for ALS
The mechanism of Aimspro remains unproven; if it is an immunomodulator and/or a modulator of sodium channels, it theoretically could be useful in ALS. A single, detailed but significantly flawed…